Increase in Lipoprotein Lipase during Clofibrate Treatment of Hypertriglyceridemia in Patients on Hemodialysis

Abstract
In 11 hypertriglyceridemic patients on hemodialysis, clofibrate (1 to 1.50 g per week) reduced plasma triglyceride (-40±20 per cent, Ps = 0.792, Ps = 0.851, Ps = 0.696, Ps = 0.679, P<0.10). There was no correlation between changes in hepatic triglyceride lipase activity and plasma lipids during treatment.