Enhancement of the lipolytic activity of skeletal muscle in certain physiological states

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Abstract
Four lipolytic enzyme preparations, whose existence was previously demonstrated in rat skeletal muscle, have been shown to be present in preparations from skeletal muscles of the golden hamster, the 13-lined ground squirrel, and three strains of mice. When compared with appropriate controls, statistically significant increases in specific activity of all four lipase preparations were observed in hibernating hamsters and muscular dystrophic mice. In obese hyperglycemic mice, three monoglyceride lipases were significantly increased; there was no significant increase, however, in tricaproin lipase. In hibernating 13-lined ground squirrels and aurothioglucose-treated hyperphagic mice, only the monopalmitin lipase was significantly increased.

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