Light and Propranolol Suppress the Nocturnal Elevation of Serotonin in the Cerebrospinal Fluid of Rhesus Monkeys
- 29 July 1983
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 221 (4609) , 474-476
- https://doi.org/10.1126/science.6683428
Abstract
Markedly elevated nighttime concentrations of serotonin in rhesus monkey cerebrospinal fluid were reduced to daytime levels by exposing the monkeys to continuous light or to the beta-adrenergic antagonist propranolol. Nighttime elevations of melatonin in cerebrospinal fluid were also suppressed by propranolol and light. Serotonin released in large quantities at night appears to be regulated like melatonin, and may act as a cerebroventricular hormone to influence brain and pituitary function at night.This publication has 28 references indexed in Scilit:
- Diurnal rhythms of serotonin in monkey cerebrospinal fluidLife Sciences, 1982
- Daily variations in serotonin metabolism in the suprachiasmatic nucleus of the rat: influence of oestradiol impregnationJournal of Endocrinology, 1982
- The effect of propranolol on the serotonin concentration in the portal plasma after vagal nerve stimulation in the catActa Physiologica Scandinavica, 1979
- Evidence that serotonin neurons stimulate secretion of prolactin releasing factorLife Sciences, 1978
- Seasonal incidence of an altered diurnal rhythm of platelet serotonin in unipolar depressionJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1978
- THE CEREBROSPINAL FLUID AS A PATHWAY IN NEUROENDOCRINE INTEGRATIONJournal of Endocrinology, 1976
- Circadian rhythm in cerebrospinal fluid noradrenaline of man and monkeyNature, 1976
- The Pharmacology of the Pineal GlandAnnual Review of Pharmacology and Toxicology, 1976
- The Pineal Gland: A Neurochemical TransducerScience, 1974
- Rapid Light-Induced Decrease in Pineal Serotonin N -Acetyltransferase ActivityScience, 1972