DEMONSTRATION OF THE FEMALE SEX HORMONE IN THE CIRCULATING BLOOD
- 15 August 1925
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 85 (7) , 510
- https://doi.org/10.1001/jama.1925.02670070030010
Abstract
In a previous paper,1we showed beyond contraversion that the follicle fluid, corpus luteum and placenta contained the same hormone, which, until its chemical nature is better defined, we denominate simply as "the female sex hormone." For the three endocrine glands involved we have coined the collective name of "gestational gland" to designate their function. Today we are able to show that the female sex hormone is present at times in demonstrable quantity in the circulating blood. No full details need be given in this preliminary communication. The literature contains few and unconvincing references to this subject. Marshall2injected the blood of estrous female dogs into anestrous female dogs and obtained faint signs of heat. Tuffier3produced (?) menstruation in two amenorrheal women by injecting 20 c.c. of blood obtained from women who were just beginning to menstruate. As our work shows that the hormone is present onlyKeywords
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