Synthetic Studies towards Vinblastine and its Analogues, VI The Markownikov Addition of Acetic Acid to Catharanthine by a Modification of the Prevost Reaction
Open Access
- 1 February 1976
- journal article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung B
- Vol. 31 (2) , 264-266
- https://doi.org/10.1515/znb-1976-0226
Abstract
The reaction of catharanthine under modified prevost reaction conditions has afforded 20-acetoxydihydrocatharanthine, an important intermediate for the synthesis of antileukaemic alkaloids, vinblastine and vincristine.Keywords
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