RELATIONSHIP BETWEEN RENIN ACTIVITY AND ALDOSTERONE RELEASE IN THE PATIENTS WITH LOW CARDIAC OUTPUT SYNDROME AFTER OPEN CARDIAC SURGERY

Publisher Website
Google Scholar
Abstract
Plasma renin activity and aldosterone concentrations were measured by radioimmunoassay technique in 7 patients with low cardiac output syndrome after open cardiac surgery. Plasma renin activity and aldosterone concentration markedly increased and plasma renin activity correlated well with plasam aldosterone concentration. Plasma renin activity and aldosterone concentration, had no direct correlation with plasma Na and K concentration or administered doses of inotropic agent, K and diuretic. Na and K balance was closely correlated with plasma aldosterone concentration. The secondary hyperaldosteronism following low cardiac output syndrome after open cardiac surgery evidently was mainly induced by the increased release of renin and it influenced the balance of Na and K metabolism under such disturbed circulatory circumstances.