Effect of increasing the plasma oxygen diffusivity on experimental cryogenic edema
- 1 November 1976
- journal article
- research article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 45 (5) , 535-538
- https://doi.org/10.3171/jns.1976.45.5.0535
Abstract
Mongrel cats with experimental cryogenic brain lesions were treated with the carotenoid compound crocetin. Crocetin increases the diffusion speed of O2 through plasma, and should provide a net increase in available O2 to the capillary endothelial cell. The treated group of animals showed a significant reduction in edema compared to a comparable control group. O2 availability is apparently an important factor in vasogenic edema.This publication has 3 references indexed in Scilit:
- Oxygen diffusion and atherosclerosisAtherosclerosis, 1974
- STEROIDS AND CEREBRAL EDEMAJournal of Neuropathology and Experimental Neurology, 1968
- The Relationship Between Edema, Blood-Brain-Barrier and Tissue Elements in a Local Brain InjuryJournal of Neuropathology and Experimental Neurology, 1958