Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2′-hydroxyphenyl)benzoxazole analogs of UK-1
- 12 November 2007
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 16 (4) , 1775-1783
- https://doi.org/10.1016/j.bmc.2007.11.019
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Evaluation of metal-mediated DNA binding of benzoxazole ligands by electrospray ionization mass spectrometryJournal of the American Society for Mass Spectrometry, 2008
- Critical structural motif for the catalytic inhibition of human topoisomerase II by UK-1 and analogsBioorganic & Medicinal Chemistry Letters, 2004
- Ni(II)·Arg-Gly-His−DNA Interactions: Investigation into the Basis for Minor-Groove Binding and RecognitionJournal of the American Chemical Society, 2004
- Synthesis and evaluation of anticancer benzoxazoles and benzimidazoles related to UK-1Bioorganic & Medicinal Chemistry, 2002
- Evaluation of complexation of metal-mediated DNA-binding drugs to oligonucleotides via electrospray ionization mass spectrometryNucleic Acids Research, 2001
- Iron chelators from mycobacteria (1954–1999) and potential therapeutic applicationsNatural Product Reports, 2000
- Mg 2+ -mediated binding of 6-Substituted quinolones to DNA: relevance to biological activityBioorganic & Medicinal Chemistry, 1998
- UK-1, a Novel Cytotoxic Metabolite from Strcptomyces sp. 517-02. III. Antibacterial Action of Demethyl UK-1.The Journal of Antibiotics, 1997
- Self-Assembly of a Quinobenzoxazine-Mg2+ Complex on DNA: A New Paradigm for the Structure of a Drug-DNA Complex and Implications for the Structure of the Quinolone Bacterial Gyrase-DNA ComplexJournal of Medicinal Chemistry, 1995
- UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.The Journal of Antibiotics, 1993