The influence of HLA‐A, B compatibility on the outcome of cadaver renal transplantation in Stockholm during 1970–1980

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Abstract
The influence of HLA-A, B-matching on the results of 362 cadaver renal transplantations was analyzed. Of these, 34 of the patients had diabetes and 105 were 55 yr old or more. The case material was divided into groups, based on the number of HLA-A, B incompatibilities. The occurrence of factors having a possible bearing on kidney graft survival was determined in each match group. Several of these factors, such as the immunosuppressive agents given and the number of high-risk patients, were unequally distributed in the various groups. This may be related to changes in policy that have occurred since the transplant unit was moved. To obtain homogeneous case material, the series that was moved was analyzed separately. A significant difference in survival was found in both materials between transplants with 2 or less incompatibilities and those with more than 2 incompatibilities. A significant difference in patient survival between these 2 groups was found in the total case material.