COMPUTER DENSITOMETRY OF RETINAL NERVE FIBRE ATROPHY

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Abstract
Lack of nerve fiber layer opacity and a granular appearance of the retina are important funduscopic signs in optic atrophy. Serially obtained fundus photographs from a case with developing optic atrophy were subjected to computer densitometry. A monotonic increase in local density variations was found during evolution of optic atrophy. The change in density variations closely followed the fundoscopic change in nerve fiber layer opacity. This method allows detection and quantification of diffuse atrophy of the retinal nerve fiber layer.

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