Predeposit Autologous Blood Transfusions in Patients Undergoing Irradiation and Radical Cystectomy

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Abstract
Blood withdrawn electively and frozen for later use by the donor was used in 25 patients with bladder cancer who were treated by preoperative irradiation and radical cystectomy. Patients donated 1-5 units of blood (average 3.4/patient). Ten patients were transfused with only autologous blood, whereas 15 required some homologous blood in addition to their own banked blood. The program was well tolerated and repeated blood donation did not compromise the effectiveness of preoperative irradiation. This program reduces the dependence on volunteer donor homologous blood transfusions for cystectomy, thus, decreasing the potential risk of an adverse reaction and avoiding seasonal blood bank shortages.