Immunity to Hymenolepis diminuta: unresponsiveness of the athymic nude mouse to infection
- 1 February 1976
- journal article
- research article
- Published by Cambridge University Press (CUP) in Parasitology
- Vol. 72 (1) , 93-97
- https://doi.org/10.1017/s0031182000058509
Abstract
Male and female congenitally athymic nude (nu/nu) mice infected with a single cysticercoid of Hymenolepis diminuta at 6 weeks of age retain the infection for at least 33 days. In the males of their phenotypically normal litter-mates, however, a single cysticercoid infection establishes and grows but is expelled between days 11 and 17. The unresponsiveness of the nude mouse to single H. diminuta infection is evidence that the immune rejection from normal mice is thymus-dependent.This publication has 23 references indexed in Scilit:
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