Cefaclor Therapy Twice Daily for Acute Otitis Media
- 1 January 1982
- journal article
- research article
- Published by American Medical Association (AMA) in American Journal of Diseases of Children
- Vol. 136 (1) , 33-35
- https://doi.org/10.1001/archpedi.1982.03970370035008
Abstract
• Cefaclor, a new orally administered cephalosporin, was used in a dose of 40 mg/kg/day for the treatment of acute otitis media in 60 children. The effectiveness and safety of this dose in a twice-daily vs thrice-daily regimen were compared. There were no differences in the clinical response between the two treatment groups. The drug was well tolerated by all patients, and no major clinical or laboratory toxic effects were observed. The twice-daily regimen did not improve compliance. (Am J Dis Child 1982;136:33-35)This publication has 5 references indexed in Scilit:
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- A pharmacological and in vitro comparison of three oral cephalosporinsJournal of Antimicrobial Chemotherapy, 1979
- Pharmacokinetics of cefaclor in infants and childrenJournal of Antimicrobial Chemotherapy, 1978
- Treatment of Acute Otitis Media of Infancy With CefaclorArchives of Pediatrics & Adolescent Medicine, 1978
- In Vitro Studies with Cefaclor, a New Oral CephalosporinAntimicrobial Agents and Chemotherapy, 1977