6-Alkyl- and 5,6-Dialkyl-2-methoxy-4(3H)-pyrimidinones in the Transformations of Pyrimidines. Conversion into 2-Substituted Amino- and 4-Chloro-Pyrimidine-Derivatives
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 15 (1) , 27-34
- https://doi.org/10.1080/00397918508063774
Abstract
6-Alkyl- and 5,6-dialkyl-2-methoxy-4(3H)-pyrimidinones are transformed into the 2-alkyl(and 2-aryl)amino-derivatives, in good yield, by reaction with the corresponding amines. Treatment with SOCl2 -DMF gives 6-alkyl- and 5,6-dialkyl-2-methoxy-4-chloro pyrimidines.Keywords
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