Complexity ofKlebsiella pneumoniaeIsolates Resistant to Both Cephamycins and Extended-Spectrum Cephalosporins at a Teaching Hospital in Taiwan

Abstract
Among 99 clinicalKlebsiella pneumoniaeisolates resistant to cefoxitin and extended-spectrum cephalosporins, coexistence of AmpC (DHA-1, CMY-2, or CMY-8) and extended-spectrum β-lactamases (CTX-M and/or SHV) was detected in a total of 35. The remainder produced AmpC (n= 42), extended-spectrum β-lactamases (n= 9), metallo-β-lactamases (n= 2), or none of these enzymes (n= 11). Phenotypic characteristics of these isolates were demonstrated.

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