The Effect of Sensitized Lymphocytes on Peritoneal Exudate Macrophages in the Guinea Pig

Abstract
Summary: The injection of antigen into the peritoneal cavity of delayed hypersensitive guinea pigs bearing peritoneal exudates leads to a marked reduction in the macrophage content of these exudates. Lymphocytes from immunized donors can confer this property on glycogen-induced exudates in non-immunized recipients. The reaction appears to represent an in vivo analog of the well-known migration inhibition reaction.

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