Calcium transport in the proximal convoluted tubule and loop of Henle of rats made diabetic with streptozotocin
- 1 December 1991
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 131 (3) , 373-380
- https://doi.org/10.1677/joe.0.1310373
Abstract
In-vivo microperfusion was used to localize the reabsorptive defect responsible for the hypercalciuria of diabetes mellitus and to investigate possible causative factors. Unidirectional proximal calcium absorption was not significantly different in rats made diabetic with streptozotocin compared with controls, providing evidence against the involvement of this nephron segment in the phenomenon. Calcium absorption by the loop of Henle, was however, significantly (PPJournal of Endocrinology (1991) 131, 373–380Keywords
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