Olfactory Organ of Channel Catfish as a Site of ExperimentalEdwardsiella ictaluriInfection
- 1 June 1994
- journal article
- Published by Oxford University Press (OUP) in Journal of Aquatic Animal Health
- Vol. 6 (2) , 101-109
- https://doi.org/10.1577/1548-8667(1994)006<0101:ooocca>2.3.co;2
Abstract
Edwardsiella ictaluri, the causative agent of enteric septicemia of catfish (ESC), is one of the most important pathogens to infect channel catfish Ictalurus punctatus. Although the full pathogenesis of E. ictaluri is unclear, the olfactory organ is thought to be a site of entry. We have examined the effects of applying E. ictaluri directly into the olfactory capsule of channel catfish. Olfactory organs of 30 experimental fish were exposed to E. ictaluri for 1 h (1 mL, 1 × 106 colony-forming units/mL). Live fish were sampled at 1, 24, 48, and 72 h, and days 5 and 14 postinfection, and their olfactory organs were examined by light and electron microscopy. Damage, including loss of sensory cilia and microvilli from the olfactory mucosal surface, was observed at 1 h postinfection. Degeneration of olfactory receptors and supporting cells was evident by 24 h postinfection. The nonsensory region also showed signs of degeneration, such as columnar cells lacking cilia. Electron microscopic immunocytochem...Keywords
This publication has 0 references indexed in Scilit: