Synthesis of a New C2-Symmetric Molecule with Dimeric Hydroxyethylene Isosteric Moiety
- 1 December 1997
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 27 (23) , 4163-4172
- https://doi.org/10.1080/00397919708005464
Abstract
As part of our studies directed toward the development of new HIV protease inhibitors, a new type of C2-symmetric molecule having a dimeric hydroxyethylene isosteric moiety is synthesised by Cu(II)-mediated dimerisation of the sodium enolate of an amino acid-derived methylketo copound.Keywords
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