Ecdysone Analog: Conversion to Alpha Ecdysone and 20-Hydroxyecdysone by an Insect
- 19 December 1969
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3912) , 1540-1541
- https://doi.org/10.1126/science.166.3912.1540
Abstract
The tritium-labeled synthetic ecdysone analog Δ7-5β-cholestene-2β,-3β,14α-triol-6-one terminated diapause when injected into diapausing tobacco hornworm pupae and was converted into tritium-labeled α-ecdysone and tritium-labeled 20-hydroxyecdysone. About half of the crystalline α-ecdysone and 20-hydroxyecdysone isolated from the tobacco hornworms 7½ to 8½ days after injection was derived from endogenous steroid precursors and half from the transformation of the synthetic ecdysone analog.Keywords
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