Acceleration Effects of Phosphine Ligands in the Nickel Catalyzed Methylation of Aldehydes Using Trimethylaluminum
- 1 October 1998
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 27 (10) , 1033-1034
- https://doi.org/10.1246/cl.1998.1033
Abstract
A nickel catalyzed methylation of aldehydes was conducted successfully using trimethylaluminum as an alkylation reagent. In the presence of a phosphine or phosphite ligand, the reaction was considerably accelerated to give the methylation product in good yields.Keywords
This publication has 13 references indexed in Scilit:
- Catalytic Asymmetric DihydroxylationChemical Reviews, 1994
- Asymmetric synthesis of isoquinoline alkaloids by homogeneous catalysisJournal of the American Chemical Society, 1986
- Preparation of Alkylnickel(II)–Phosphine Complexes by Reactions of Ni(acac)2 with Alkylaluminums in the Presence of Tertiary PhosphineBulletin of the Chemical Society of Japan, 1982
- Nickel-catalyzed conjugate addition of organoaluminum acetylides to .alpha.,.beta.-enonesJournal of the American Chemical Society, 1978
- Stereoselective organometallic alkylation reactions. IV. Organolithium and organoaluminum addition to trimethyl-, triphenyl-, and trichloroaluminum complexes of 4-tert-butylcyclohexanone and 2-methylcyclopentanoneThe Journal of Organic Chemistry, 1975
- Nickel-catalysed conjugate addition of trimethylaluminium to α,β-unsaturated ketonesAustralian Journal of Chemistry, 1975
- Exhaustive C-methylation of ketones by trimethylaluminiumAustralian Journal of Chemistry, 1974
- Exhaustive C-methylation of carboxylic acids by trimethylaluminium: A new route to t-butyl compoundsAustralian Journal of Chemistry, 1974
- Stereoselective alkylation reactions. I. Organomagnesium and organoaluminum addition to 4-tert-butylcyclohexanone. Unusual stereoselectivity involving trimethylaluminum alkylation in benzeneThe Journal of Organic Chemistry, 1972
- Quaternary carbons by the alkylation of tertiary halides with aluminum alkyls. Model for initiation and termination in cationic polymerizationThe Journal of Organic Chemistry, 1970