Subacute sclerosing panencephalitis

Abstract
Vascular osmiophilic deposits of entangled tubular profiles were demonstrated by electron-microscopy in the cerebral tissue of a patient with subacute sclerosing panencephalitis. Measles viral antigen, IgG, IgM, and C3 were found in the same distribution, indicating that the deposits represent immune complexes. To our knowledge, this is the first demonstration of immune complexes in the vessels of the central nervous system.

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