Novel inhibitors of leishmanial dihydrofolate reductase
- 10 April 2001
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 11 (8) , 977-980
- https://doi.org/10.1016/s0960-894x(01)00089-0
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- The leishmaniases as emerging and reemerging zoonosesPublished by Elsevier ,2000
- Design, Synthesis, and Evaluation of Inhibitors of Trypanosomal and Leishmanial Dihydrofolate ReductaseJournal of Medicinal Chemistry, 1999
- LeishmaniasisThe Lancet, 1999
- The structure-based design and synthesis of selective inhibitors of trypanosoma cruzi dihydrofolate reductaseBioorganic & Medicinal Chemistry Letters, 1999
- Recent advances in identifying and validating drug targets in trypanosomes and leishmaniasTrends in Microbiology, 1999
- Dihydrofolate reductase: A potential drug target in trypanosomes and leishmaniaJournal of Computer-Aided Molecular Design, 1998
- Structure of and kinetic channelling in bifunctional dihydrofolate reductase–thymidylate synthaseNature Structural & Molecular Biology, 1994
- Structure-based inhibitor design by using protein models for the development of antiparasitic agents.Proceedings of the National Academy of Sciences, 1993
- Selective inhibition of Leishmania dihydrofolate reductase and Leishmania growth by 5-benzyl-2,4-diaminopyrimidinesMolecular and Biochemical Parasitology, 1988
- Structure-activity relationships of dihydrofolated reductase inhibitorsChemical Reviews, 1984