Regioselective hydrolysis of aromatic dinitriles using a whole cell catalyst
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 13,p. 1679-1687
- https://doi.org/10.1039/p19940001679
Abstract
A series of aromatic dinitriles have been examined as substrates for an immobilised whole cell Rhodococcus sp. that catalyses the hydrolysis of nitrites to amides and/or carboxylic acids. The fluorinated aromatic dinitriles 48 and 49 were regioselectively hydrolysed to the corresponding cyano amides 48a and 49a whereas the non-fluorinated analogues 41–44 were converted to cyano acids but with poorer regioselectivity.Keywords
This publication has 0 references indexed in Scilit: