Novel version of Multiple Antigenic Peptide allowing incorporation on a cysteine functionalized lysine tree
- 1 July 1992
- journal article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 40 (1) , 7-12
- https://doi.org/10.1111/j.1399-3011.1992.tb00098.x
Abstract
A novel version of Multiple Antigenic Peptide (MAP) is described. This approach consists of the synthesis of a properly functionalized antigen carrier and the incorporation, on request, of one or more activated antigenic peptides. This method was to synthesize a MAP containing eight epitopes of Hsp 70‐1 from Plasmodium falciparum. Mice immunised with this MAP gave a specific response while those immunised with the peptide alone did not.Keywords
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