Combination chemotherapy with carboplatin and bleomycin for advanced and recurrent head and neck cancer: A phase II study
- 1 November 1988
- journal article
- clinical trial
- Published by Wiley in Journal of Surgical Oncology
- Vol. 39 (3) , 215-216
- https://doi.org/10.1002/jso.2930390318
Abstract
Carboplatin is a platinum analogue with activity reported in head and neck cancer. We conducted a phase II trial with 14 patients who had recurrent head and neck cancer. They were treated with carboplatin 300 mg/m2 intravenously (I.V.) and bleomycin 30 units I.V. every 4 weeks. No responses were observed in this group of patients. Dose intensity of carboplatin administration may be an important determinant of response.Keywords
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