Evaluating New Antimalarial Drugs against Trophozoite Induced Plasmodium Cynomolgi Malaria in Rhesus Monkeys
- 1 January 1976
- journal article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 25 (1) , 26-33
- https://doi.org/10.4269/ajtmh.1976.25.26
Abstract
An antimalarial drug testing system is described which utilizes trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys. The schizonticidal activity of standard antimalarial drugs in this system is reported. The system accurately predicted anti-malarial activity in man of 8 of 9 compounds selected for clinical trials.Keywords
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