Measurement of Lactate Extraction Ratio by Centrifugal Analyzer to Assess Myocardial Ischemia
Open Access
- 1 January 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 67 (1) , 80-83
- https://doi.org/10.1093/ajcp/67.1.80
Abstract
Townsend, Ronald M., Gotelli, George, Weingartner, Donys, and Marton, Laurence J.: Measurement of lactate extraction ratio by centrifugal analyzer to assess myocardial ischemia. Am J Clin Pathol 67: 80–83, 1977. The measurement of blood lactate to determine myocardial lactate extraction ratio requires a high degree of within-run precision, since small changes between arterial and coronary sinus lactate may occur. These changes in man may take place at lactate levels in the normal range, 5–18 mg/dl (0.56–2.00 mmol/l). The authors have developed a method for blood lactate determination utilizing commercially available reagents in a centrifugal analyzer (Centrifichem). Within-run precision in the low normal range, 5.4 mg/dl (0.60 inmol/l), showed a coefficient of variation of 7%. Precision extends to 50 mg/dl (5.55 mmol/l), and agreement with blood lactate values obtained with the Dupont ACA is good.This publication has 0 references indexed in Scilit: