Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells.
- 1 February 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (2) , 653-656
- https://doi.org/10.1073/pnas.74.2.653
Abstract
Chromatin proteins from [murine] erythroleukemia cells transformed by Friend virus [FL cells] were analyzed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis. A new chromosomal protein, apparent MW 25,000, appeared during erythroid differentiation of the cells induced by dimethyl sulfoxide or hexamethylenebisacetamide. This protein is tightly bound to the chromatin and does not appear to be related to any of the known histones. This protein is not induced in a dimethyl sulfoxide-resistant variant of these cells.Keywords
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