Optical Resolution of α-Ethylbenzylamine and Its Application as a Resolving Agent

Abstract
(±)-α-Ethylbenzylamine ((±)-1) was efficiently resolved into a pair of enantiomers by fractional crystallization as its cis-2-benzamidocyclohexanecarboxylic acid (2) salt. Moreover, it was found that each of both enantiomers was obtained by mutual resolution between (±)-1 and (±)-2. The optically active amine (1) was substantially capable of resolving a variety of chiral carboxylic acids.

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