INHIBITION OF PROPIONIBACTERIA BY ANTIBIOTIC AND ANTIMICROBIAL AGENTS1,2

Abstract
A suitable technique was developed to determine the antibiotic sensitivity of Propionibacterium. Then, inhibition patterns of 30 strains of 11 different Propionibacterium species against 39 antibiotic or antimicrobial agents were obtained. Propionibacteria were resistant to penicillinase-resistant penicillins such as cloxacillin, nafcillin, oxacillin, and a naphtheridine derivative nalidixic acid. Moderate sensitivity to kanamycin and colistin was shown. Only a few strains of propionibacteria were inhibited by gantrisin ( sulfisoxazole), one of nine sulfonamides tested. Determination of sensitivity to antibiotic and antimicrobial agents would not assist in speciation of this genus.

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