Spontaneous Amyloidosis of Mammals

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Abstract
Spontaneous amyloidosis is known in more than 30 mammalian species. Various patterns of mammalian amyloidosis are reviewed. On the basis of the anatomical distribution of the amyloid deposits a distinction is made between patterns with typical amyloid distribution, patterns with atypical distribution, and so-called intermediate or mixed patterns. Staining, histochemical, and electron microscopic properties of amyloid and possible etiological factors of amyloidosis in different mammalian species are briefly discussed.