Correlation Between Serum IgE and Specific IgE Antibody Titer to House Dust Mite in Children with Asthma
- 1 January 1988
- journal article
- research article
- Published by Taylor & Francis in Journal of Asthma
- Vol. 25 (1) , 7-13
- https://doi.org/10.3109/02770908809070975
Abstract
Using the enzyme-linked immunosorbent assay (ELISA) for IgE specific to mites, we evaluated the relationship between total serum IgE levels and IgE antibodies specific to mite in 58 asthmatic children. Our results showed that there was a positive correlation between total serum IgE and IgE antibody specific to Dematophagoides pteronyssinus (r = 0.57; p < 0.001) and Dermatophagoides farinae (r = 0.59; p < 0.001). There was also a significant correlation between Dermatophagoides pteronyssinus-specific IgE and farinae-specific IgE (r = 0.68; p < 0.001). This suggests that there are common allergens between the two species. The close correlation between the ELISA assay and skin test suggests that the former will be useful for the diagnosis of mite allergy in asthma.Keywords
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