RADIOTHERAPY IN THE MANAGEMENT OF CRANIOPHARYNGIOMAS

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Abstract
The results of treatment in 12 children and 14 adults with craniopharyngiomas are reported.Of 10 patients treated by a planned surgical-radiotherapeutic approach (Ist Series) I adult and 6 children are alive and well 13½ to 15 years after treatment without evidence of recurrence or brain damage. Three adults have died of intercurrent disease at 2, Jo and 14 years after treatment.Of 16 patients irradiated more recently (2nd Series) 6 were referred only after recurrence following surgical treatment. Four of 6 children (I recurrent tumor) and 7 of 10 adults (4 recurrent tumors) are alive and well 6 months to 8 years and 10 months after treatment without evidence of recurrence or brain damage.Radiation therapy after surgical biopsy and cyst evacuation appears to offer the best chance of long-term control for craniopharyngiomas.

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