Leukocyte Esterase Activity and Nitrite Test as a Rapid Screen for Significant Bacteriuria

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Abstract
The results of a simple, inexpensive reagent strip test for the detection of leukocyte esterase and nitrite in 252 urine specimens were compared with semiquantitative urine cultures. Negative reagent strip results predicted correctly all urine culture results with less than 105 CFU/mL. Screening of urine specimens with the Chemstrip® L/N could aid in reducing the cost of laboratory testing.