More on Blood Transfusion and AIDS

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To the Editor: Curran and colleagues (Jan. 12 issue)1 incriminate transfusion of blood and blood fractions as a risk factor for acquisition of the acquired immunodeficiency syndrome (AIDS). Their evidence, although compelling, depends on an analysis that many may find difficult to follow. A more straightforward approach would be to compare the actual frequency of transfusion histories among patients who have AIDS with that which would have been expected in the absence of any relation. Unfortunately, survey data that directly address the frequency of transfusion histories in the U.S. population do not exist (Feldman J: personal communication).An indirect approach . . .

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