Treatment of Painful Diabetic Neuropathy with Topical Capsaicin

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Abstract
To the Editor: Diabetic neuropathy can be accompanied by painful dysesthesias refractory to treatment.1 , 2 Another type of painful dysesthesia — postherpetic neuralgia — can be safely and effectively treated with topical capsaicin cream.3 , 4 The characteristics and proposed pathophysiologic mechanisms of the pain associated with postherpetic neuralgia are similar to those of the pain of diabetic neuropathy. This report describes two patients with painful diabetic neuropathies who were treated successfully with capsaicin cream.A 67-year-old man with a long history of diabetes mellitus that was well controlled with oral hypoglycemic therapy presented with a history of pain of one week's duration . . .

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