ROLE OF BETA-ADRENERGIC RECEPTORS IN THE ANTI-DEPRESSANT ACTIVITY OF ALPRAZOLAM

  • 1 January 1982
    • journal article
    • letter
    • Vol. 36  (2) , 329-332
Abstract
Chronic i.v. reserpine significantly increased .beta.-adrenergic receptors (.beta.-AR) in the cerebral cortex of rats. This increase in .beta.-AR is partially blocked by chronic treatment with alprazolam. Similar effects were not observed with diazepam. .beta.-AR may be involved in the antidepressant activity of alprazolam.

This publication has 1 reference indexed in Scilit: