Primary Structure of the Hemoglobins from the Greater Kudu Antelope(Tragelaphus strepsiceros)

Abstract
The adult greater Kudu antelope has 2 Hb components, Hb A and Hb B, with 1 .alpha. and 2 .beta. chains. The complete amino-acid sequences of these 3 chains are presented. The 2 .beta. chains differ only in 1 residue at position 16 (Gly .fwdarw. Ser) and may be the product of 2 allelic genes. The primary structure of the chains was determined by sequencing the tryptic peptides after their isolation from the tryptic digest of the chains by high performance liquid chromatography. The alignment of these peptides was deduced from homology with the chains of bovine Hb. Between the Kudu Hb and those of cattle a high degree of homology was found.