Increased central alpha2-adrenoceptor sensitivity in panic disorder
- 1 September 1986
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 90 (2) , 268-269
- https://doi.org/10.1007/bf00181255
Abstract
Cardiovascular responses to an intravenous challenge dose of clonidine (1.5 μg/kg) were measured in eight patients with DSM III panic disorder. In comparison with an age- and sex-matched control population panic patients showed significantly greater falls in systolic and diastolic blood pressure, with similar falls in heart rate. These observations support the view of a biological abnormality in panic disorder.This publication has 8 references indexed in Scilit:
- A cognitive approach to panicBehaviour Research and Therapy, 1986
- Effects of azepexole and clonidine on baroreceptor mediated reflex bradycardia and physiological tremor in man.British Journal of Clinical Pharmacology, 1985
- Noradrenergic Function in Panic AnxietyArchives of General Psychiatry, 1984
- Ideational Components of Anxiety: Their Origin and ContentThe British Journal of Psychiatry, 1984
- Treatment of PhobiasArchives of General Psychiatry, 1983
- The primate locus coeruleus and effects of clonidine on opiate withdrawal.1982
- Lactate Metabolism in Anxiety NeurosisNew England Journal of Medicine, 1967
- Delineation of two drug-responsive anxiety syndromesPsychopharmacology, 1964