Cotrifazid – An Agent against Malaria
- 1 January 1996
- journal article
- research article
- Published by S. Karger AG in Chemotherapy
- Vol. 42 (6) , 391-401
- https://doi.org/10.1159/000239472
Abstract
Following the brief information on a new malaria treatment with the fixed multiple combination Cotrifazid (rifampicin + isoniazid + sulfamethoxazole + trimethoprim) in Chemotherapy [1995;41:396–398], very good results are reported for the treatment of 61 patients with various forms of malaria. The tolerance was found to be good. Some relevant fundamental considerations (chemoresistance, synergism/antagonism, fixed multiple combination, switching from monotherapy to combination therapy) and the implementation of the principle of a ‘multidisease therapy’ are discussed.Keywords
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