Immune Complex Glomerulonephritis in a Case of Retroperitoneal Fibrosis

Abstract
Katz, Sheila Moriber, Bates, Ollice, Yudis, Melvin, Falkner, Bonita, and Griffith, Eleanor: Immune complex glomerulonephritis in a case of retroperitoneal fibrosis. Am J Clin Pathol 67: 436–439, 1977. The nephropathology associated with retroperitoneal fibrosis has been commonly related to compression of the ureters and hydronephrosis. This assumption has been made without the use of immunofluorescent microscopy and electron microscopy. The authors studied renal tissue from a patient with retroperitoneal fibrosis by light microscopy, immunofluorescent microscopy and electron microscopy. In addition to the gross and microscopic changes of obstructive nephropathy, histologic findings of glomerular immunecomplex deposition were also present. It is postulated that in some cases of retroperitoneal fibrosis, destruction may be mediated by both obstructive and immunologic processes.

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