In-Vitro Blood Compatibility Studies on a New Polymer-Coated Charcoal for Haemoperfusion

Abstract
The blood compatibility of a new polyhema-coated charcoal (Biotec) has been studied in an in-vitro haemoperfusion circuit. The mean inlet platelet levels after 4 hours of perfusion were 99.5 ± SE 4.2% of the initial value and mean white cell levels were 81.9 ± SE 5.8% of initial. No rises in Swank screen filtration pressure were detected. Initial evaluation of this charcoal in patients with fulminant hepatic failure should be possible without platelet-protective agents.