Biological reaction to debris in relation to joint prostheses
- 1 February 1997
- journal article
- review article
- Published by SAGE Publications in Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
- Vol. 211 (2) , 187-197
- https://doi.org/10.1243/0954411971534304
Abstract
Bone loss induced by the inflammatory response to wear particles is a major cause of long-term failure of total joint replacement. This review describes the cellular reaction occurring in response to these particles and what is currently known about the inflammatory mechanisms contributing to bone resorption.Keywords
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