Histologic processes of healing in hepatic injury due to eggs of Schistosoma mansoni in mice following curative chemotherapy *
- 1 March 1973
- journal article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 22 (2) , 211-214
- https://doi.org/10.4269/ajtmh.1973.22.211
Abstract
In mice, whose infections with Schistosoma mansoni were terminated by treatment with the nitrovinylfuran derivative, trans-5-amino-3-[2-(5-nitro-2-furyl)-vinyl]l,2,4-oxadiazole (SQ 18,506), the hepatic injury due to eggs of these parasites was almost completely reversed. The sequence of histologic events leading to healing of these schistosomal lesions are divided into six morphologically distinct stages and the characteristic features of each are described and illustrated.Keywords
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