NONSYPHILITIC INTERSTITIAL KERATITIS WITH VESTIBULOAUDITORY SYMPTOMS

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Abstract
IN 1945 I described 4 patients presenting a syndrome consisting of a characteristic type of interstitial keratitis and vestibuloauditory symptoms like those of Ménière's disease and resulting, usually, in complete deafness.1Only 1 previous instance, and this one questionable, could be found from an examination of the literature. The ocular signs consisted early of a granular type of corneal infiltrate, patchy in distribution, situated predominantly in the posterior half of the cornea; late the cornea became vascularized. The keratitis was bilateral in 3 of the 4 patients and ran a characteristically chronic course, varying in its severity from day to day and from eye to eye. There was little or no reaction in the anterior chamber or the iris. The vestibuloauditory symptoms, coming on within a few days of the ocular symptoms, consisted typically of severe vertigo, tinnitus, nystagmus and rapidly progressive deafness. There was an elevated white blood

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