THE INTRAMUCOSAL CYSTS OF THE STOMACH .5. THE INTRAMUCOSAL CYSTS OF THE STOMACH IN JAPANESE SUBJECTS HAVING FOCAL (ELEVATED) DYSPLASIA

  • 1 January 1983
    • journal article
    • research article
    • Vol. 74  (3) , 391-397
Abstract
The frequency of intramucosal cysts underneath focal (elevated) neoplastic lesions (which include epithelial dysplasia and early gastric cancer) was recorded in 88 resected stomachs. The mean cyst index (i.e., the amount of intramucosal cysts per area of gastric mucosa) underneath such lesions was 30.9 (SD .+-. 16.9), while in adjacent normal-looking gastric mucosa it was 9.4 (SD .+-. 8). The difference was significant (P < 0.001). The cyst index was highest in female patients, underneath focal (elevated) dysplasias. Previous work indicated that the normal-looking gastric mucosa in Japanese patients with peptic ulcer disease was 3.4 (SD .+-. 6.6). The present findings appear to suggest that cystic formation in gastric mucosa may herald an early neoplastic growth at the luminal aspect in some of the cysts.