Enzymes in organic synthesis. 44. Stereoselective pig liver esterase-catalyzed hydrolyses of 3-substituted glutarate diesters of compactin-synthon interest
- 1 June 1988
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 66 (6) , 1422-1424
- https://doi.org/10.1139/v88-229
Abstract
Pig liver esterase-catalyzed hydrolyses of dimethyl 3-hydroxy-, 3-methoxyethoxymethoxy-, and 3-benzyloxyglutarates occur with enantiotopic stereoselectivity to give the corresponding acid-ester products of 16–40% enantiomeric excess (ee). The results also provide another example of reversal of PLE-stereoselectivity.Keywords
This publication has 0 references indexed in Scilit: