Long- and short-term regulation of feeding patterns in the rat.

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Abstract
Analysis of feeding patterns in rats showed that the amount of food eaten in relatively long intervals (24-72 h) was correlated with mean meal size and was essentially uncorrelated with meal frequency. The regulatory adjustment in daily food intake occurring in response to changes in environmental temperature was the result of an adjustment in mean meal size, with no change in meal frequency. The amount of food eaten in relatively short intervals (3-12 h) was more highly correlated with meal frequency than with mean meal size, and a reliable correlation between meal size and the postmeal interval was obtained. The meal size/postmeal interval regression equation predicted the long-term relation between mean meal size and the amount of food eaten. Meal frequency was apparently controlled largely by short-term regulatory signals and at least some long-term regulatory signals affected meal size directly.

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