The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target
- 1 April 2009
- journal article
- research article
- Published by Taylor & Francis in Cancer Biology & Therapy
- Vol. 8 (7) , 618-626
- https://doi.org/10.4161/cbt.8.7.7923
Abstract
Pancreatic cancer is a near uniformly lethal disease and a better understanding of the molecular basis of this malignancy may lead to improved therapeutics. The Axl receptor tyrosine kinase is impl...Keywords
This publication has 71 references indexed in Scilit:
- Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic AnalysesScience, 2008
- The human receptor tyrosine kinase Axl gene – promoter characterization and regulation of constitutive expression by Sp1, Sp3 and CpG methylationBioscience Reports, 2008
- Growth arrest-specific gene 6 expression in human breast cancerBritish Journal of Cancer, 2008
- Pancreatic CancerAnnual Review Of Pathology-Mechanisms Of Disease, 2008
- TAM Receptor Tyrosine Kinases: Biologic Functions, Signaling, and Potential Therapeutic Targeting in Human CancerPublished by Elsevier ,2008
- GTP‐binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoBioEssays, 2007
- Patterns of somatic mutation in human cancer genomesNature, 2007
- Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid CancersCancer Research, 2007
- Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survivalProceedings of the National Academy of Sciences, 2006
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodMethods, 2001